It will save many dangerous snakes from being bitten: Scientists have created a universal antidote

Snakes are dangerous creatures, they kill tens of thousands of people every year, and there is no antidote to the bites of the most dangerous of them. However, a new development developed by scientists has radically changed the rules of the game.

Scientists at Scripps Research have developed a synthetic antibody that could be a major breakthrough in treating snake bites worldwide, particularly bites from elapids, a family of snakes that includes some of the most venomous species known to man. This family includes snakes such as cobra, mamba and krait, which are responsible for a significant portion of snakebite deaths, reaching 138,000 annually. However, New Atlas writes that a new development by researchers aims to significantly reduce this alarming figure.

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The traditional method of producing antidote uses animals to produce antibodies against the poison. This process is controversial due to many ethical issues, dangers, and possible allergic reactions in humans. Trying to overcome these challenges, the research team turned its attention to a common toxin found in elapid venom, known as 3FTx. These toxins primarily cause paralysis in snakebite victims.

After analyzing the venom proteins of different elapid species, the researchers found similarities in the 3FTx proteins in different snakes. They then set out to look for an antibody that could neutralize this toxin. Their search led them to a library of more than 50 billion synthetic human antibodies, from which they isolated an antibody called 95Mat5. The study found that the antibody was effective against the venom of many deadly snakes, including the many-striped snake and the black mamba, and protected against paralysis and death in preliminary animal tests.

95Mat5 is a monoclonal antibody, meaning it is produced synthetically, eliminating the need for animal donors and snake venom in its production. This not only solves ethical issues, but also reduces the risk of injury and allergic reactions in people receiving the antidote.

However, scientists warn that 95Mat5 is not a magic bullet that can save us from all snake bites, as snake venom consists of a complex and diverse mixture of toxins. To create a truly universal antidote, a combination of antibodies that simultaneously target many toxins found in the venoms of different snakes would be required. For now, the team is focused on identifying additional antibodies to increase the effectiveness of their antivenom and potentially cover a wider range of snake venoms.

The discovery of 95Mat5 is an important step in the search for a universal cure for fatal snake bites. The fact that this research will potentially save lives and prevent disability on a global scale underscores the power of science and its constant innovation to help us combat even the most terrifying and dangerous external factors.

Previously Focus He wrote about the ten largest snakes in the world. From the legendary anaconda that inspired a series of horror movies in the ’90s to the incredibly diverse species of python, this list features some truly terrifying giant creatures and interesting facts about them and other snakes.

Moreover Focus wrote about a new species of bird that spits out a powerful neurotoxin. At high concentrations it can cause severe convulsions and even death.

This material is for informational purposes only and does not contain advice that may affect your health. If you are having problems, contact an expert.

Source: Focus

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