Many of us, at least once in our lives, felt the burden of fractures that deprived us of the ability to work normally. But for a certain category of people, such situations become a daily reality, turning their lives into hell.
Type 2 diabetes (T2DM) affects many organs in our body, leading to a variety of serious complications, including kidney failure, cardiovascular disease, nerve damage, and an increased risk of fractures. A recent study found that although people with T2DM generally have higher bone mineral density (BMD), paradoxically, they are at higher risk of bone fractures due to deteriorating bone quality, News Medical writes.
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A study of 3,008 women ages 75 to 80, published in JAMA Network Open, found that people with T2DM had higher BMD at the hip and lumbar spine, but their bones had weaker microarchitecture, making them more prone to fractures.
This unusual phenomenon is probably due to factors that negatively affect bone strength, such as accumulation of advanced glycation end products, decreased bone turnover, and changes in fatty deposits in the bone marrow.
In addition to bone health, the study found that women with T2DM also had significantly worse physical function. They had weaker grip strength, slower walking speed, and took longer to initiate movement compared with their non-diabetic peers. Long-term insulin therapy exacerbated these physical deficits, despite the higher BMD levels observed in this group.
The study also noted that poor glycemic control in T2DM increased the risk of death and fractures, particularly hip fractures. Women with the highest glycated hemoglobin (HbA1C) levels, which indicate poor blood sugar control, had a significantly higher risk of fractures, even after adjusting for other risk factors such as age and weight.
Diabetes has a significant impact on our entire body; its complications go beyond glucose metabolism to include weakening of bone structure and reduced physical function of the body.
Comprehensive and timely treatment of T2DM is critical to reduce these risks and prevent progression of complications in the various affected organs.
Previously Focus He wrote that humanity will experience a wave of diabetes by 2050. From millions to billions: New research reveals the dire future of diabetes worldwide by 2050 unless health systems act proactively.
Moreover Focus wrote that diabetes affects brain damage. Recent studies have shown that patients with type 1 diabetes experience premature brain aging.
Important! This article is based on the latest scientific and medical research and does not contradict it. The text is for informational purposes only and does not contain medical advice. Be sure to consult a doctor for diagnosis.
Source: Focus
Ashley Fitzgerald is an accomplished journalist in the field of technology. She currently works as a writer at 24 news breaker. With a deep understanding of the latest technology developments, Ashley’s writing provides readers with insightful analysis and unique perspectives on the industry.