We slow down aging. Scientists talk about science achievements in anti-aging medicine

The field of anti-aging research is evolving and new treatments are constantly being developed. Let’s take a look at some of the latest and promising developments in delaying aging.

The aspects of anti-aging medicine are quite diverse. Experts are studying both new pharmacological agents and the influence of the environment, our actions, the impact of various diets and sleep on the aging rate of our body.

Let’s start with anti-aging drugs that can be effective:

1. Cenolytics

Cenolytics are effective in treating the causes of aging and can prevent a wide variety of age-related diseases.

They work by destroying senescent cells, i.e. damaged cells that stop dividing but refuse to die. The Epoch Times writes that with age, aging cells accumulate in the foci of many chronic disorders and diseases. They can release a wide variety of potentially harmful or inflammatory molecules that damage surrounding tissues.

Removing senescent cells has been shown to slow aging, treat age-related diseases, and prolong “health time.”

Unlike average life expectancy, which is the total number of years a person has lived, “wellness” is how many of these years a person would be considered healthy and disease-free.

Some widely studied senolytic compounds that are easy to obtain from your diet include:

Fisetin is a plant flavonoid found in many fruits and vegetables, including strawberries, apples, onions and grapes.

Quercetin, another plant-based flavonol found in onions, red wine, green tea, apples and fruits.

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2. Metformin

There is ample evidence that metformin, a diabetes drug derived from a compound found in the common French lilac, may do more than help patients improve their blood sugar levels.

The drug may even slow aging, according to a critical 2021 study.

A recent review of studies concluded that metformin’s efficacy in reducing signs of biological aging “reflects its potency and potential as a therapeutic agent that can act on important mechanisms of aging.”

A 2021 review of studies revealed that the drug may not have this effect in people without diabetes, but its ability to reduce premature deaths associated with diseases such as diabetes, cancer, cardiovascular disease and cognitive decline may improve our health and prolong lifespan. during our lifetime.

It is important to remember that metformin is a prescription drug and can have side effects such as nausea, vomiting and diarrhea. It should only be used under the supervision of a doctor.

3. NAD+ Precursors

NAD+ is an essential molecule for life and health. It plays a role in energy metabolism, DNA repair, and cell survival or death.

Aging is accompanied by a gradual decrease in NAD+ levels in our bodies.

This decline has been associated with several age-related diseases, including cognitive decline, cancer, metabolic disease, and frailty. NAD+ precursors are compounds we can take to increase the levels of this important substance in our bodies.

They contain various forms of vitamin B3 (niacin) – nicotinamide riboside and nicotinamide mononucleotide – and are found in some foods.

Nicotinamide riboside can be found in cow’s milk, and nicotinamide mononucleotide occurs naturally in foods such as edamame beans, broccoli, cabbage, cucumbers, and avocados.

The Anti-Aging Diet: Calorie Restriction

A first-of-its-kind randomized controlled trial by an international team of researchers shows that calorie restriction can slow the rate of aging in healthy adults.

Aging rate was measured by participants’ DNA methylation (the process of adding a methyl group to DNA). The effect measured was equivalent to a 2-3 percent reduction in the rate of aging.

Previous research confirms that even modest reductions in the rate of aging can have significant public health implications.

Calen Ryan, a research fellow at Columbia University’s Butler Center on Aging and co-author of the study, says the study found evidence that calorie restriction slows the rate of aging in humans, but that may not be true for everyone.

“Our findings are important because they provide randomized trial evidence that it is possible to slow human aging. They also give us insight into the types of effects we can look for in intervention trials that could attract more people,” Ryan said in a statement. It’s like intermittent fasting or time-restricted eating.”

Strange noted that there is not a single drug or class of drugs that significantly slows the aging process and is approved for such use.

It’s important to note that while these advances are promising, most are still in the early stages of research and have yet to be fully tested and proven in human trials.

However, maintaining healthy habits is one of the most effective ways to increase life expectancy and improve overall health.

The main components of a healthy lifestyle include:

A diet rich in fruits, vegetables, whole grains and lean protein can help reduce the risk of chronic diseases such as heart disease, diabetes and certain types of cancer.

Physical activity is critical for maintaining health and increasing life expectancy. Regular exercise can help improve cardiovascular health, maintain a healthy weight, and reduce the risk of chronic disease.

Chronic stress can negatively affect physical health and increase the risk of developing chronic disease. Finding healthy ways to manage stress, such as meditation, yoga or regular exercise, can help reduce stress levels and improve overall health.

Adequate sleep is essential for maintaining good health. Aim for seven to nine hours of quality sleep each night and avoid staying up late or using electronic devices before bed, as this can affect sleep quality.

Smoking and binge drinking are two unhealthy habits that can dramatically shorten your health and increase your risk of chronic disease and cancer. Quitting smoking and limiting alcohol consumption can have a positive effect on overall health, increasing both health and life expectancy.

“What we eat, staying physically and mentally active, and taking care of ourselves are the best ways to slow down the aging process,” said Strange.

Previously Focus He wrote about different ways to slow down aging. The study shows that simply reducing calories will not only reduce the rate of aging, but also the risk of death.

Source: Focus

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