After conducting a large-scale study, scientists managed to identify several genes that accumulate calcium, previously unknown to science; this may suggest a way to treat a dangerous disease.
Heart disease is one of the main problems of developed countries. First on the comprehensive list is coronary heart disease. It is caused by plaque buildup on the artery walls called atherosclerosis. So far, science has discovered only a few genes associated with this disease. According to New Atlas, at this point, a group of experts stepped in to examine the genetic reasons for its formation in more depth.
Focus.Technology has its own technology. telegram channel. Subscribe to avoid missing the latest and most exciting news from the world of science!
The presence of calcium in the coronary arteries, which carry blood to the heart, is often a warning sign; It is an early sign of coronary heart disease (CHD). Interestingly, calcium accumulation is not only related to diet or lifestyle but also to our genes. In fact, 30-40% of the risk comes from our genetics.
One of the key participants in the research, Dr. Clint Miller said: “We knew some of the genes associated with this condition from previous research, but it was clear that we were only scratching the surface of an incredibly deep iceberg. We needed larger, more comprehensive studies.” “To really understand the genetics of calcium accumulation.”
A team of scientists conducted a large-scale study examining the genetic data of more than 35,000 people. They found 43 potential genes associated with calcium accumulation. Their most interesting discovery was that eight of these genes were completely new in the context of calcium deposition, and five had never been associated with CAD before.
One of these genes, called ENPP1, is even altered in rare cases of arterial calcification in infants. Researchers also discovered genes that play a role in a specific pathway known to stop artery calcification. However, researchers were not satisfied with identifying these genes; They wanted to make sure they found exactly the genes they needed. Therefore, they conducted additional studies on tissues and cells of human heart arteries and confirmed the direct effect of these genes on calcium deposition and related processes.
However, some of these genes may interact with certain medications and even nutritional supplements such as vitamins C and D. This means we may have tools to control or prevent calcium buildup in our arteries.
Of course, further research is needed. Scientists have not yet reached the stage in their studies where they can safely introduce new treatment methods. However, these results provide new opportunities for predicting the risk of developing coronary artery disease and for early intervention to prevent its progression.
Dr. Miller is optimistic about the future. “This project shows how powerful large-scale studies can be. We hope to be able to translate these early results into real-world treatments in the future. We also look forward to finding more genes that can help us make predictions.” “The risk of developing CAD in different situations,” he says.
Previously Focus He wrote about how you can prevent heart disease without leaving your home. In a large-scale study, scientists found that the activity that is many people’s daily companion can strengthen our hearts and potentially save us from premature death.
Moreover Focus He wrote that scientists were able to observe the first seconds of the heart starting in the embryo. Scientists have learned many interesting facts by examining the first seconds of the heart’s life in a young embryo; for example, that the heart starts working before it is formed.
This material is for informational purposes only and does not contain advice that may affect your health. If you are having problems, contact an expert.
Source: Focus
Ashley Fitzgerald is an accomplished journalist in the field of technology. She currently works as a writer at 24 news breaker. With a deep understanding of the latest technology developments, Ashley’s writing provides readers with insightful analysis and unique perspectives on the industry.