Tiny pests in our brains: Scientists discovered a new source of Alzheimer’s disease

In a groundbreaking study led by Northwestern University, scientists have made a major discovery that could change our understanding and treatment of diseases such as Alzheimer’s disease and other types of dementia. Researchers have discovered small RNA molecules in the brain that play a critical role in the health of our brain cells. ScienceAlert writes that these molecules can protect cells or cause them to die, and this balance can change with age, potentially leading to Alzheimer’s disease.

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RNA, or ribonucleic acid, is the substance in our cells that carries instructions from DNA to create the proteins our body needs. However, not all RNAs are involved in the protein production process. Some of the short RNA strands the study focused on help regulate protein production. This regulation is necessary for our cells to stay healthy.

Researchers found a shift towards more toxic RNA molecules in the brains of older people, especially those with Alzheimer’s disease. These harmful RNAs can stop the production of vital proteins and lead to cell death in a process known as DISE (death caused by destruction of survival genes). Interestingly, this process is also a protective mechanism against cancer, which may explain why cancer rates are lower in Alzheimer’s patients.

One of the most interesting aspects of this research is the study of people over the age of 80 who have extraordinary memory abilities, what scientists call “superheroes.” These superheroes had higher levels of protective RNA in their brains, suggesting that these molecules play a role in their cognitive resilience.

The study used a variety of methods to explore these findings, including analysis of human brain tissue and experiments with mice. This discovery is particularly exciting because it could lead to a new approach to treating Alzheimer’s disease and other neurodegenerative diseases. It may be possible to prevent or delay the onset of these diseases by increasing the levels of protective RNAs in the brain.

This research opens new avenues for drug development, going beyond the traditional focus on amyloid plaques and tau bonds characteristic of Alzheimer’s disease. Targeting the balance of RNA molecules instead may offer a new and promising strategy for preserving brain health in old age.

The implications of this scientific study are broad: It suggests that we could potentially intervene in the aging process of our brain cells. By strengthening protective RNA in the brain, we can preserve our cognitive health for longer and fight diseases that currently have no cure.

This research not only sheds light on the complex mechanisms underlying neurodegenerative diseases, but also offers hope for new treatments that could significantly improve the quality of life of older adults and those suffering from diseases such as Alzheimer’s disease.

Previously Focus He wrote about a new drug for Alzheimer’s disease that showed unprecedented results. The drug showed an impressive ability to slow the progression of the disease, but it also had some very serious side effects.

Moreover Focus He wrote that you can fight Alzheimer’s disease with food. One study has shown that a person with Alzheimer’s disease can significantly improve their condition by changing their approach to eating.

This material is for informational purposes only and does not contain advice that may affect your health. If you are having problems, contact an expert.