With the help of artificial intelligence, scientists have created the first map of a group of proteins known as the Commander protein complex. New understanding of the functions of these proteins will aid in the development of drugs for the treatment of Alzheimer’s disease and cancer.
A team of scientists used artificial intelligence to create a first-of-its-kind map of a protein complex called Commander. According to the researchers, these proteins work as a “mail service” in the human body. The New Atlas writes that a better understanding of the functions of these proteins will aid in the development of drugs for the treatment of Alzheimer’s disease, other types of dementia, infectious diseases and cancer.
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A group of 16 proteins found in the human body, called the Commander protein complex, have many biological functions, according to a new study published in the journal Cell. Specifically, these proteins strengthen the body’s immune response, maintain cell homeostasis, and act as a kind of delivery and steering system.
Just as postal companies have processes for transporting and sorting cargo, scientists say there are molecular machines in human cells that transport and sort proteins. The Commander Protein Complex controls this delivery system to ensure the right amount of protein reaches the right place.
Scientists have also found that this protein complex is associated with many diseases, including viral diseases, certain types of cancer, and neurodegenerative diseases. In particular, this complex is involved in the transport of amyloid protein, which contributes to the development of Alzheimer’s disease.
The scientists decided to investigate the nature of this protein complex in more detail and created the first 3D map to better understand its structure. To do this, the researchers used the new electron microscope in conjunction with machine learning algorithms. Thus, a detailed visualization of all 16 proteins that make up the protein complex was obtained.
The authors of the study believe that with the help of this map it is possible to trace the link between this protein complex and many diseases, which will help to look for ways to combat them. One of the results of the study showed that all the proteins in the Commander complex work together to perform their functions. The discovery could mean that previous research into the effects of individual proteins needs to be reconsidered, the scientists say.
As already written FocusThe scientists found a link between the Western diet and the risk of Alzheimer’s disease, and also found potential preservatives in the form of omega-3s and probiotics.
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Important! This article is based on and does not contradict the latest scientific and medical research. The text is for informational purposes only and does not contain medical advice. Be sure to see a doctor for a diagnosis.
Source: Focus
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